✦ LIBER ✦

Determination of urinary acylcarnitines by ESI-MS coupled with solid-phase microextraction (SPME)

✍ Scribed by Möder, Monika; Löster, Heinz; Herzschuh, Rainer; Popp, Peter

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 405 KB
Volume: 32
Category: Article
ISSN: 1076-5174
DOI: 10.1002/(sici)1096-9888(199711)32:11<1195::aid-jms578>3.0.co;2-9

No coin nor oath required. For personal study only.

✦ Synopsis

The determination of selected short-, medium-and long-chain acylcarnitines by electrospray ionization mass spectrometry (ESI-MS) is discussed. The di †erences in fragmentation behaviour and ionization efficiency are described in dependence on collision induced dissociation (CID) conditions and mixture composition. A new method combination, solid-phase microextraction (SPME)-ESI-MS, is introduced to characterize acylcarnitines in body Ñuids. This method utilizes SPME for pre-concentration of acylcarnitines from complex biological samples and ESI-MS for a selective and sensitive detection. The method is presented by standard experiments determining of acylcarnitines in aqueous solutions and urine samples from patients with secondary carnitine deÐciency syndromes or related disorders.

📜 SIMILAR VOLUMES

Determination of Urinary Mercury and Met

Determination of Urinary Mercury and Methylmercury by Solid Phase Microextraction and GC/MS

✍ Guidotti, Maurizio ;Vitali, Matteo 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 29 KB

Fully automated determination of N-nitro

Fully automated determination of N-nitrosamines in environmental waters by headspace solid-phase microextraction followed by GC–MS–MS

✍ Anna Llop; Francesc Borrull; Eva Pocurull 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 200 KB 👁 1 views

## Abstract A fully automated method for determining nine Environmental Protection Agency __N__‐nitrosamines in several types of environmental waters at ng/L levels is presented. The method is based on a headspace solid‐phase microextraction followed by GC–MS–MS using chemical ionization. Three dif

Selective determination of alkylmercury

Selective determination of alkylmercury compounds in solid matrices after subcritical water extraction, followed by solid-phase microextraction and GC–MS

✍ Andreas Beichert; Susanne Padberg; Bernd W. Wenclawiak 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 62 KB 👁 2 views

Determination of thiol compounds by auto

Determination of thiol compounds by automated headspace solid-phase microextraction with in-fiber derivatization

✍ Qing Wang; J. Michael Chong; Janusz Pawliszyn 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 481 KB 👁 1 views

Solid-phase microextraction–liquid chrom

Solid-phase microextraction–liquid chromatography (SPME–LC) determination of lamotrigine simultaneously with carbamazepine and carbamazepine 10,11-epoxide in human plasma

✍ M. E. C. Queiroz; S. M. Silva; D. Carvalho; Fernando M. Lanças 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 83 KB 👁 1 views

Determination of partition coefficient a

Determination of partition coefficient and analysis of nitrophenols by three-phase liquid-phase microextraction coupled with capillary electrophoresis

✍ Mohd Marsin Sanagi; Mazidatulakmam Miskam; Wan Aini Wan Ibrahim; Dadan Hermawan; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 237 KB

## Abstract A three‐phase hollow fiber liquid‐phase microextraction method coupled with CE was developed and used for the determination of partition coefficients and analysis of selected nitrophenols in water samples. The selected nitrophenols were extracted from 14 mL of aqueous solution (donor so