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Determination of unbound prednisolone, prednisone and cortisol in human serum and saliva by on-line solid-phase extraction liquid chromatography tandem mass spectrometry and potential implications for drug monitoring of prednisolone and prednisone in saliva

✍ Scribed by A. F. C. Ruiter; N. Teeninga; J. Nauta; E. Endert; M. T. Ackermans


Book ID
112013406
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
646 KB
Volume
26
Category
Article
ISSN
0269-3879

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## Abstract A method based on solid‐phase extraction coupled to liquid chromatography with positive ion electrospray ionization and tandem mass spectrometric detection was developed for the determination of didanosine in human serum, using lamivudine as internal standard. The acquisition was perfor