Determination of Trivalent Methylated Arsenicals in Biological Matrices
β Scribed by Luz Maria Del Razo; Miroslav Styblo; William R. Cullen; David J. Thomas
- Book ID
- 112268401
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 143 KB
- Volume
- 174
- Category
- Article
- ISSN
- 0041-008X
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π SIMILAR VOLUMES
Biomethylation is considered a major detoxification pathway for inorganic arsenicals (iAs). According to the postulated metabolic scheme, the methylation of iAs yields methylated metabolites in which arsenic is present in both pentavalent and trivalent forms. Pentavalent mono- and dimethylated arsen
## Abstract Arsenic is a prevalent human carcinogen whose mutagenicity has not been characterized fully. Exposure to either form of inorganic arsenic, As^III^ or As^V^, can result in the formation of at least four organic metabolites: monomethylarsonic acid, monomethylarsonous acid (MMA^III^), dime