Determination of the primary structure and carboxyl pKAs of heparin-derived oligosaccharides by band-selective homonuclear-decoupled two-dimensional1H NMR

Improved resolution in two-dimensional 1

Improved resolution in two-dimensional 1H NMR spectra of peptides by band-selective, homonuclear decoupling during both the evolution and acquisition periods: application to characterization of the binding of peptides by heparin

✍ Jing Wang; Dan Borchardt; Dallas L. Rabenstein 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 436 KB

## Abstract Two‐dimensional ^1^H NMR experiments that achieve band‐selective, homonuclear decoupling in both the indirectly detected F1 and directly detected F2 dimensions were used to assign the highly overlapped ^1^H NMR spectrum of the peptide Ac‐SRGKARVRAKVKDQTK‐NH~2~, both free in solution and