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Determination of the maximum specific uptake capacities for glucose and oxygen in glucose-limited fed-batch cultivations of Escherichia coli

✍ Scribed by H. Y. Lin; B. Mathiszik; B. Xu; S.-O. Enfors; P. Neubauer

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 258 KB
Volume: 73
Category: Article
ISSN: 0006-3592
DOI: 10.1002/bit.1068

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## Abstract Overflow metabolism is an undesirable characteristic of aerobic cultures of __Escherichia coli__. It results from elevated glucose consumption rates that cause a high substrate conversion to acetate, severely affecting cell physiology and bioprocess performance. Such phenomenon typicall