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Determination of the enantiomers of zopiclone and its two chiral metabolites in urine using an automated coupled achiral—chiral chromatographic system

✍ Scribed by Christine Fernandez; François Gimenez; Bruno Baune; Valérie Maradeix; Alain Thuillier; Robert Farinotti

Publisher
Elsevier Science
Year
1993
Weight
397 KB
Volume
617
Category
Article
ISSN
0378-4347

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Although gas chromatography/mass spectrometry (GC/MS) is the most powerful technique for analysing cocaine and its hydrolysis products (benzoylecgonine, ecgonine methyl ester and ecgonine) in urine, the sample pretreatment required is rather laborious and involves a large number of steps. This paper