Determination of the enantiomeric purity of scopolamine isolated from plant extract using achiral/chiral coupled column chromatography

Enantiomeric Determination of the Phenyl

Enantiomeric Determination of the Phenylmorpholinol Metabolite of Bupropion in Human Plasma Using Coupled Achiral–Chiral Liquid Chromatography

✍ Raymond F. Suckow; Ming F. Zhang; Thomas B. Cooper 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB 👁 2 views

A coupled achiral-chiral stationary phase liquid chromatographic technique was developed to separate and quantitate the enantiomers of the phenylmorpholinol metabolite (2) of the antidepressant bupropion (1) in human plasma. At the retention time of 2, a switching valve loaded a portion of the eluti