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Determination of the enantiomeric composition of carprofen by proton nuclear magnetic resonance spectroscopy with a chiral lanthanide-shift reagent

✍ Scribed by George M. Hanna; Cesar A. Lau-Cam


Book ID
118995284
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
440 KB
Volume
36
Category
Article
ISSN
0039-9140

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Determination of the enantiomeric purity
✍ J. Belleney; C. Bui; F. J. Carriere πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 481 KB

## Abstract The enantiomeric purities of disubstituted β‐lactams were determined by ^1^H and ^13^C NMR spectroscopy using tris[3‐(trifluoromethylhydroxymethylene)‐d‐camphorato]europium(III), Eu(tfc)~3~, as a chiral shift reagent. Using a [Eu(tfc)~3~]/[lactam] ratio of 0.5, most of the resonances we