## Abstract The solution conformation of the macrolide antibiotic kijanimicin (1) was deduced by a combination of NMR spectroscopy and potential energy calculations of the carbohydrate parts using the HSEA force field. The study was based on temperature dependent NMR spectroscopic shift data, 1D nu
Determination of the Conformation of the 2′OH Group in RNA by NMR Spectroscopy and DFT Calculations
✍ Scribed by Dipl.-Chem. Senada Nozinovic; M. Sc. Puneet Gupta; Dr. Boris Fürtig; Dr. Christian Richter; Dipl.-Chem. Sandor Tüllmann; Dr. Elke Duchardt-Ferner; Prof. Dr. Max C. Holthausen; Prof. Dr. Harald Schwalbe
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 546 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
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## Abstract The absence of HH couplings between the methoxy group and the ring protons observed in 2‐methoxy‐, 2,6‐dimethoxy‐ and 2‐methoxy‐6‐chloropyridines is interpreted in terms of a __cis__ conformation between the methyl fragment and the nitrogen ring atom. Other data, taken from the current