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Determination of the concentration scaling law of the scattering coefficient of water solutions of Intralipid at 832 nm by comparison between collimated detection measurements and Monte Carlo simulations

✍ Scribed by Maddalena Autiero; Raffaele Liuzzi; Patrizia Riccio; Giuseppe Roberti


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
161 KB
Volume
36
Category
Article
ISSN
0196-8092

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✦ Synopsis


Abstract

Background and Objectives

Intralipid (IP) is a scatterer extensively used in the building of phantoms for Biomedical Optics measurements. Recently, deviations from the linearity have been shown for the concentration scaling law of the scattering coefficient of IP water solutions at visible wavelengths. In this work this scaling law was determined at 832 nm.

Study Design/Materials and Methods

Space resolved transmittance measurements of a laser beam at 832 nm through water solutions of IP and ink were performed and compared with the corresponding results of Monte Carlo simulations.

Results

The comparison provides a quadratic dependence of μ on the volume‐to‐volume scatterer concentration, C~IP~, in the range of C~IP~ values (0.0024<C~IP~<0.0075). These deviations from the linear behavior are related to the failure of the independent scatterer approximation.

Conclusion

The quadratic dependence of on C~IP~ is in agreement with recent results obtained by other groups with different experimental techniques and is validated by a recent theoretical work. © 2005 Wiley‐Liss, Inc.