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Determination of the average molecular weight of nonionic emulsifiers by vapor-phase osmometry

โœ Scribed by France Guay; Suzanne Bisaillon

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
320 KB
Volume
73
Category
Article
ISSN
0022-3549

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โœฆ Synopsis

Three families of alloxan derivatives, 5-arylthiobarbituric, 5-aryliminobarbituric, and 5-aryldialuric acids, were prepared as prospective radioiodine-transporting radiopharmaceuticah for the delineation of pancreatic insulinomas. Members of each class were screened for effects on blood sugar levels in a rat glucove tolerance assay. Transient hyperglycemia was observed with 5-(2,4-dichlorophenyl)iminobarbituric acid. No agent evaluated induced permanent diabetes at the doses tested.

Keyphrases Alloxan-analogues, potential tumor-imaging agents, pancreatic insulinomas, effect on blood glucose levels, rats 0 Tumorimaging agents-alloxan analogues, pancreatic insulinomas, effect on blood glucose levels, rats

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