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Determination of the absolute stereochemistry of vitamin E derived oxa-spiro compounds by NMR spectroscopy

✍ Scribed by Harald Schröder; Thomas Netscher


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
240 KB
Volume
39
Category
Article
ISSN
0749-1581

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✦ Synopsis


Abstract

This contribution describes the structure elucidation of dimeric and trimeric oxidation products derived from natural (2__R__,4′R,8′R)‐α‐ and (2__R__,4′R,8′R)‐γ‐tocopherol, the most important lipid‐soluble vitamin E compounds and antioxidants in biological systems. Complete ^1^H and ^13^C NMR signal assignments have been obtained by combinations of one‐ and two‐dimensional NMR techniques. These structural investigations include full determination of stereochemistry and a study of dynamic processes. Copyright © 2001 John Wiley & Sons, Ltd.