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Determination of residual solvents in pharmaceutical products by gas chromatography coupled to a head-space injection system and using an external standard

✍ Scribed by J.P. Guimbard; M. Person; J.P. Vergnaud


Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
743 KB
Volume
403
Category
Article
ISSN
1873-3778

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✦ Synopsis


A method of determination of residual solvents in powders using gas chromatography with an head-space injection system has been developed. The chromatographic conditions and parameters of the injection system were optimized to enable the quantification by external standardization of most common solvents in concentrations ranging from a few ppm to a few per cent.