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Determination of (R)- and (S)-Disophyramide in human plasma using a chiral α1-acid glycoprotein column

✍ Scribed by Jörgen Hermansson; Märit Eriksson; Olof Nyquist

Book ID
108449969
Publisher
Elsevier Science
Year
1984
Weight
485 KB
Volume
336
Category
Article
ISSN
0378-4347

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Evaluation of a hydrazide-linked α1-acid
Evaluation of a hydrazide-linked α1-acid glycoprotein chiral stationary phase: Separation of R- and S-propranolol
✍ Hai Xuan; David S. Hage 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 961 KB

## Abstract The binding and chiral separation of __R__‐ and __S__‐propranolol was investigated on a new type of α~1~‐acid glycoprotein (AGP) column. This column was prepared through the controlled and mild oxidation of AGP, followed by the immobilization of this protein to hydrazide‐activated silic