Determination of protein rotational correlation time from NMR relaxation data at various solvent viscosities

Determination of the Rotational Diffusio

Determination of the Rotational Diffusion Tensor of Macromolecules in Solution from NMR Relaxation Data with a Combination of Exact and Approximate Methods—Application to the Determination of Interdomain Orientation in Multidomain Proteins

✍ Ranajeet Ghose; David Fushman; David Cowburn 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 335 KB

In this paper we present a method for determining the rotational diffusion tensor from NMR relaxation data using a combination of approximate and exact methods. The approximate method, which is computationally less intensive, computes values of the principal components of the diffusion tensor and es