Determination of potassium in pharmaceutical formulations by means of 18-crown-6: Extraction studies

✍ Scribed by Maria Augusta Raggi; Luciano Nobile; Michela Ramini; Ilaria Perboni

• Book ID: 103911206
• Publisher: Elsevier Science
• Year: 1989
• Tongue: English
• Weight: 388 KB
• Volume: 7
• Category: Article
• ISSN: 0731-7085
• DOI: 10.1016/0731-7085(89)80163-3

✦ Synopsis

A colorimetric method has been developed for the determination of potassium in pharmaceutical formulations. The method is based on the formation of a complex of potassium with 18-crown-6, followed by conversion to an ion-pair with picrate anion; the ion-pair is extracted with either methylene chloride or toluene-methylene chloride (80:20, v/v) and determined colorimetrically.