Determination of Polyethylene Glycols 4000 and 6000 in Plasma Protein Preparations
✍ Scribed by B. Skoog
- Book ID
- 115108129
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 273 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0042-9007
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## Abstract The solubility of plasma proteins was studied at various pH as a function of polyethylene glycol concentration. Computer analysis of precipitation curves permitted equations to be derived. The equations describe the relationship between protein solubility and polyethylene glycol concent
The dissolution characteristics of dicumarol were markedly enhanced by preparing dispersions of drug in polyethylene glycol 4000. Solid dispersions of varying weight fractions were formed by a melt method without measurable drug degradation or evaporation. There were no significant differences in di