Determination of partition coefficients of non-ionic contrast agents by reversed-phase high-performance liquid chromatography

✍ Scribed by Ignacio J. Alonso-Silva; Jose M. Carretero; Jose L. Martin; Antonio M. Sanz

• Publisher: Elsevier Science
• Year: 1990
• Tongue: English
• Weight: 495 KB
• Volume: 507
• Category: Article
• ISSN: 1873-3778
• DOI: 10.1016/s0021-9673(01)84206-0

✦ Synopsis

Reversed-phase high-performance liquid chromatography was used to measure the lipophilicities of non-ionic contrast agents. Calculated partition coefficients were correlated with the capacity factors extrapolated to zero organic modifier content. ' AC = Acetyl. b (L) = Chiral center configuration of the lactoyl group.