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Determination of P-gp and MRP1 expression and function in peripheral blood mononuclear cells in vivo

✍ Scribed by E.R Meaden; P.G Hoggard; S.H Khoo; D.J Back


Book ID
114050980
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
135 KB
Volume
262
Category
Article
ISSN
0022-1759

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## Abstract The aim of the study was to evaluate the mRNA expression of four relevant ABC‐transporter genes [MDR1 (P‐glycoprotein; Pgp), MRP1, MRP4, and MRP5] in HIV‐positive individuals failing treatment and analyze the association between the levels of their expression and viral load, CD4 cell co