Large volume leukapheresis (LVL) reduces the number of procedures required to obtain adequate peripheral blood progenitor cells (PBPCs) for autologous hematopoietic reconstitution. LVL involves the processing of >15 L or 5 patient blood volumes using high flow rates. We report our experience with LV
Determination of optimal timing of peripheral blood progenitor-cell collection in children
β Scribed by R.A. Anderson; T.R. Corr; K.R. Schultz; B.G. Massing; J.H. Davis; C.J.H. Fryer
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 157 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0009-9120
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β¦ Synopsis
F'OS!l'ER ABSTRACTS =0.69), and with pre-harvest bD34+ count (r= 0.56). Peripheral Blood (PB) CD340t cell count and leukocyte count correlated poorly with the CD34+ cell count and CPU-GM of the collected product. We conclude that good correlation exists between PB leukocyte and CD34+ cell count with leukapheresis product MNC count. This warrants continued usage of these parameters to guide collection of PBPC's.
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## Abstract There is increasing demand for mononuclear cell (MNC) harvests not only for PBPC but also for immune therapies using dendritic cells and donor lymphocytes. We determined the collection efficiencies (CE) of various MNC subpopulations during CD34^+^ cell harvests using a Fenwal CS 3000 Pl
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