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Determination of mexidole content in blood serum by HPLC using Elsicon concentration columns

✍ Scribed by I. I. Miroshnichenko; S. Yu. Kuz'mina; L. D. Smirnov

Book ID
112713772
Publisher
Springer
Year
1994
Tongue
English
Weight
171 KB
Volume
28
Category
Article
ISSN
0091-150X

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## Abstract A simple and direct analysis using column‐switching HPLC method was developed and validated for the quantification of active metabolites of sibutramine, __N__‐mono‐desmethyl metabolite (metabolite 1, M1) and __N__‐di‐desmethyl metabolite (metabolite 2, M2) in the serum of rats administe