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Determination of meclocycline, a tetracycline analogue, in cream formulations by liquid chromatography

โœ Scribed by Anneli M. Depaolis; Thomas E. Britt; Arlene J. Holman; Eugene J. McGonigle; Gerald Kaplan; Walter C. Davies

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
237 KB
Volume
73
Category
Article
ISSN
0022-3549

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A simple liquid chromatographic (LC) method was developed for the determination of tetracyclines (oxy-tetracycline, tetracycline and chlortetracycline) in animal tissues. Isolation of tetracyclines from biological matrices was performed with oxalic buffer followed by dechelation and deproteinization