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Determination of ligand conformation in macromolecular complexes using the transferred nuclear overhauser effect

✍ Scribed by Angela M. Gronenborn; G.Marius Clore

Book ID
115781472
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
574 KB
Volume
40
Category
Article
ISSN
0006-2952

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Uncertainties in structural determinatio
Uncertainties in structural determinations of oligosaccharide conformation, using measurements of nuclear Overhauser effects
✍ E. Wrenn Wooten; Christopher J. Edge; Renzo Bazzo; Raymond A. Dwek; Thomas W. Ra πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier Science 🌐 English βš– 277 KB

A fundamental problem in the determination of molecular structure by n.m.r. spectroscopy is insufficient experimental constraints. This problem is particularly marked for oligosaccharides, where few constraints are available across glycosidic linkages. By calculating distances as a function of dihed