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Determination of kynurenine in serum by high-performance liquid chromatography after enzymatic conversion to 3-hydroxykynurenine

✍ Scribed by Junko Naito; Isao Ishiguro; Toshinobu Murazumi; Makoto Morimoto

Book ID
107714527
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
345 KB
Volume
161
Category
Article
ISSN
0003-2697

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Determination of serum kynurenine and he
Determination of serum kynurenine and hepatic tryptophan dioxygenase activity by high-performance liquid chromatography
✍ Earle W. Holmes πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 English βš– 693 KB

The status of the oxidative metabolism of L-tryptophan is usually evaluated by the determination of tryptophan metabolites in serum or urine and/or the activities of various oxidative enzymes in tissues. I have developed assays for serum kynurenine and hepatic tryptophan dioxygenase (TDO) activity b