Blood-brain barrier penetration of 3-ami
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AndrΓ©n, Per E.; Emmett, Mark R.; DaGue, Beverly B.; Steulet, Anne-FranΓ§oise; Wal
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Article
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1998
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John Wiley and Sons
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English
β 340 KB
π 1 views
The detection and quantitation of the novel drug 3-aminopropyl-n-butylphosphinic acid (APBP), also known as CGP 36742, was performed in vivo using microdialysis and tandem mass spectrometry. This drug is a GABA-B antagonist with high speciΓcity for GABA-B receptors. Animals received doses of 100, 20