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Determination of intracellular pH using sensitive, clickable fluorescent probes

✍ Scribed by Nazmiye B. Yapici; Srinivas Rao Mandalapu; Teng-Leong Chew; Satya Khuon; Lanrong Bi

Book ID
113496698
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
569 KB
Volume
22
Category
Article
ISSN
0960-894X

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## Abstract The intracellular pH (pHi) of a series of cancer cell lines was determined using the pH‐sensitive indicators imidazole (Im) or histidine (His) and diffusion‐weighted (DW) proton NMR spectroscopy. The DW method allows the observation at high magnetic field gradient values of only the slo