Insulin-like growth factor-I prevents ca
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Delaney, Catherine L. ;Cheng, Hsin-Lin ;Feldman, Eva L.
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Article
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1999
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John Wiley and Sons
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English
β 100 KB
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Both neurons and glia succumb to programmed cell death (PCD) when deprived of growth factors at critical periods in development or following injury. Insulin-like growth factor-I (IGF-I) prevents apoptosis in neurons in vitro. To investigate whether IGF-I can protect Schwann cells (SC) from apoptosis