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Determination of insulin-like growth factor-I effect on apoptosis in CHO cells in biopharmaceutical production

✍ Scribed by Somayeh Piroozmand; Mehran Miroliaei; Mohammad Atyabi; Homan Kaghazian; Jamal Moshtaghian


Book ID
118431438
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
73 KB
Volume
44
Category
Article
ISSN
0009-9120

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Insulin-like growth factor-I prevents ca
✍ Delaney, Catherine L. ;Cheng, Hsin-Lin ;Feldman, Eva L. πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 100 KB πŸ‘ 2 views

Both neurons and glia succumb to programmed cell death (PCD) when deprived of growth factors at critical periods in development or following injury. Insulin-like growth factor-I (IGF-I) prevents apoptosis in neurons in vitro. To investigate whether IGF-I can protect Schwann cells (SC) from apoptosis