Determination of imipenem in human plasma, urine and tissue by high-performance liquid chromatography

✍ Scribed by G. Carlucci; L. Biordi; C. Vicentini; M. Bologna

• Publisher: Elsevier Science
• Year: 1990
• Tongue: English
• Weight: 346 KB
• Volume: 8
• Category: Article
• ISSN: 0731-7085
• DOI: 10.1016/0731-7085(90)80038-q

✦ Synopsis

A simple and reliable HPLC method is described for the new beta-lactam antibiotic imipenem; suitable extraction procedures for the drug in human plasma, urine and prostatic tissue are described. The figures of merit for the assays are reported and examples given of their application.