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Determination of idebenone in rat serum and brain by high-performance liquid chromatography using platinum catalyst reduction and electrochemical detection

โœ Scribed by Hiroyuki Wakabayashi; Masaharu Nakajima; Susumu Yamato; Kenji Shimada

Publisher
Elsevier Science
Year
1992
Weight
225 KB
Volume
573
Category
Article
ISSN
0378-4347

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A new, sensitive, and specific assay method for guanine nucleotides using high-performance liquid chromatography with dual-electrochemical detection was developed. GTP, GDP, GMP, and cyclic GMP were separated with reversed-phase "ion-pair" chromatography and detected by a dual-electrochemical detect