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Determination of human liver cytochrome P-450 level by electron paramagnetic resonance of liver biopsies

✍ Scribed by Luc Garbrielle; François Leterrier; Pierre Cristau; Charles Laverdant


Book ID
115820669
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
508 KB
Volume
60
Category
Article
ISSN
0009-8981

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## Abstract Cytochrome P450 (CYP) substrates that yield fluorescent metabolites were used for rapid screening of drug metabolism activities of 13 recombinant human cytochromes P450, human liver microsomes and human hepatocytes. Reproducible results were obtained using a fluorescent plate reader (Cy