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Determination of HIV-1 susceptibility to reverse transcriptase (RT) inhibitors by a quantitative cell-free RT assay

โœ Scribed by Greene, Richard A.; Japour, Anthony J.; Brewster, Frank; Joseph, Richard A.; Chung, Pei H.; Kasila, Patricia A.; Chatis, Pamela A.


Book ID
122964208
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
659 KB
Volume
7
Category
Article
ISSN
0928-0197

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## Abstract It has been reported that a new pattern of mutations, E44D/A and/or V118I, in the reverse transcriptase (RT) gene of HIVโ€1 confers a moderate level of resistance to lamivudine in the absence of the M184V mutation. The prevalence of this mutational pattern was studied in HIVโ€1 isolates o