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Determination of higher aliphatic amines and cyclohexylamine by TLC after derivatization with 1-fluoro-2,4-dinitrobenzene

✍ Scribed by A. Jegorov; J. Tříska; H. Zahradníčková


Book ID
112291785
Publisher
Springer
Year
1990
Tongue
English
Weight
232 KB
Volume
338
Category
Article
ISSN
1618-2650

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✍ F.A.L. Van Der Horst; J. Teeuwsen; J.J.M. Holthuis; U.A.Th. Brinkman 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 364 KB

Cationic micelles have been used for the derivatization of the anti-Parkinson drug amantadine with the chromophore 1-fluoro-2,4-dinitrobenzene in urine. In the presence of 90 mM cetyltrimethylammonium bromide (CTAB), the conversion of amantadine into its derivative is complete within 4 min at 60 deg