Haemophilia A: Carrier detection by DNA
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Schwaab, R. ;Oldenburg, J. ;Higuchi, M. ;Ludwig, M. ;Kochhan, L. ;Horst, J. ;Bra
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Article
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1988
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Springer-Verlag
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From 46 families of predominantly German origin, afflicted with haemophilia A, 178 females were tested for carrier status. Two polymorphic restriction endonuclease sites, the extragenic marker locus DXS 52 (St 14 probe) and the intragenic Bcl I RFLP were investigated in these families. In some cases