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Determination of haemophilia A carrier status by mutation analysis

โœ Scribed by S. Oranwiroon; V. Akkarapatumwong; P. Pung-Amritt; A. Treesucon; G. Veerakul; C. Mahasandana; S. Panyim; P. Yenchitsomanus


Book ID
108769394
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
176 KB
Volume
7
Category
Article
ISSN
1351-8216

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Haemophilia A: Carrier detection by DNA
โœ Schwaab, R. ;Oldenburg, J. ;Higuchi, M. ;Ludwig, M. ;Kochhan, L. ;Horst, J. ;Bra ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer-Verlag โš– 638 KB

From 46 families of predominantly German origin, afflicted with haemophilia A, 178 females were tested for carrier status. Two polymorphic restriction endonuclease sites, the extragenic marker locus DXS 52 (St 14 probe) and the intragenic Bcl I RFLP were investigated in these families. In some cases