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Determination of guanosine tetraphosphate (ppGpp) and adenosine pentaphosphate (pppApp) in various microorganisms by radioimmunoassay

✍ Scribed by Yasutaro Hamagishi; Akihiro Yoshimoto; Toshikazu Oki


Book ID
104762851
Publisher
Springer
Year
1981
Tongue
English
Weight
398 KB
Volume
130
Category
Article
ISSN
0302-8933

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✦ Synopsis


The intracellular levels of ppGpp and pppApp in various microorganisms ~were determined by radioimmunoassay, which was of more accuracy and convenience than previous 32p-labeling method. PPGPP was detected in bacteria, actinomycetes, yeasts and fungi, pppApp was found in non-spore forming bacteria such as the genera Pseudomonas and Escherichia, fungi and actinomycetes, but not in yeasts. In conclusion, ppGpp and pppApp are present in various prokaryotes and lower eukaryotes.