Failure to identify tobacco- or heroin-exposed neonates is extensive owing to the limitations of current methods used to verify maternal drug use. Maternal self-reported drug history has been shown to be unreliable: many women who deny use during pregnancy exhibit drug metabolites in their urine. Ma
✦ LIBER ✦
Determination of gestational opiate, nicotine, benzodiazepine, cocaine and amphetamine exposure by hair analysis
✍ Scribed by P. Kintz; P. Mangin
- Publisher
- Elsevier
- Year
- 1993
- Tongue
- English
- Weight
- 397 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0015-7368
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## Abstract A simple liquid chromatography–electrospray ionization mass spectrometry (LC‐ESI‐MS) method for the determination of nicotine and cotinine in human hair was established. In the procedure, a hair sample (10 mg) was washed with dichloromethane and digested in 2.5 m sodium hydroxide. The d