Determination of Folic Acid by Adsorptive Stripping Voltammetry at a Lead Film Electrode

✍ Scribed by Mieczyslaw Korolczuk; Katarzyna Tyszczuk

• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 57 KB
• Volume: 19
• Category: Article
• ISSN: 1040-0397
• DOI: 10.1002/elan.200703969

✦ Synopsis

Abstract

An adsorptive stripping voltammetric procedure for the determination of folic acid at an in situ plated lead film electrode was described. Formation of lead film on a glassy carbon substrate and accumulation of folic acid was performed simultaneously from an acetate buffer solution of pH 5.6 at the potential −0.88 V. The measurements were carried out from aerated solutions. The calibration graph for an accumulation time of 300 s was linear from 2×10^−9^ to 5×10^−8^ mol L^−1^. The detection limit was 7×10^−10^ mol L^−1^, the relative standard deviation for 2×10^−8^ mol L^−1^ of folic acid was 3.9%. The proposed procedure was applied to folic acid determinations in pharmaceutical preparations.