Enantioselective determination of isradi
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Heidi S. Rask; Helle R. Angelo; Hanne R. Christensen
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Article
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1998
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John Wiley and Sons
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English
β 154 KB
π 2 views
rac-Isradipine is a dihydropyridine type calcium antagonist. Its calcium entry blocking effect is due primarily to the (+)-(S)-enantiomer. This study describes a sensitive enantioselective method for the determination of isradipine in human serum. Following alkaline extraction into hexane, the enant