Determination of p-Nitrophenol Hydroxyla
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R.J. Duescher; A.A. Elfarra
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Article
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1993
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Elsevier Science
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English
⚖ 294 KB
p-Nitrophenol hydroxylation to p-nitrocatechol is a useful metabolic marker for the presence of functional cytochrome \(P 4502 E 1\) in mammalian cell microsomes, but the assay is limited by the sensitivity of the spectrophotometric method used to monitor p-nitrocatechol formation. In this paper, a