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Determination of enantiomeric purity by simultaneous dual circular dichroism and ultraviolet spectroscopy

✍ Scribed by Péter Horváth; András Gergely; Béla Noszál


Book ID
117224139
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
126 KB
Volume
44
Category
Article
ISSN
0039-9140

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A new sensitive, selective, and versatile circular dichroism (CD)-based HPLC detection system was used for the validation of the enantiomeric purity assay in the quality control of chiral drugs upon nonchiral stationary phases. The precision and the accuracy of the method were checked for selected s