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Determination of drugs from urine by on-line immunoaffinity chromatography—high-performance liquid chromatography—mass spectrometry

✍ Scribed by Geoffrey S. Rule; Jack D. Henion


Book ID
107996967
Publisher
Elsevier Science
Year
1992
Weight
627 KB
Volume
582
Category
Article
ISSN
0378-4347

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An immunoaffinity chromatography extraction capillary liquid chromatography separation has been coupled to electrospray ionization mass spectrometry for on-line characterization of drug metabolites of a therapeutic peptide in plasma. It is demonstrated that the selectivity, sensitivity and molecular