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Determination of dissociation constants of some pharmaceutical compounds using derivative spectrophotometry

✍ Scribed by I. I. Hewala; F. A. El-Yazbi; A. Awad; A. M. Wahbi

Book ID
114738346
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
340 KB
Volume
17
Category
Article
ISSN
0269-4727

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πŸ“œ SIMILAR VOLUMES

Determination of dissociation constants
Determination of dissociation constants of sparingly soluble phenothiazine derivatives by second-derivative spectrophotometry
✍ Keisuke Kitamura; Miharu Takenaka; Sachiyo Yoshida; Mariko Ito; Yuriko Nakamura; πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 English βš– 329 KB

The dissociation constants (pK,) for sparingly soluble phenothiazines (promazine, chlorpromazine, trifluoropromazine) in water were measured by second-derivative spectrophotometry. The intense background signals in the absorption spectra due to the turbidity caused by the precipitation of insoluble