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Determination of dependence of binding parameters on receptor occupancy—A correction

✍ Scribed by Aldo Rescigno; James S. Beck; H. Joseph Goren

Book ID
108393492
Publisher
Springer
Year
1983
Tongue
English
Weight
42 KB
Volume
45
Category
Article
ISSN
1522-9602

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Determination of dependence of binding p
Determination of dependence of binding parameters on receptor occupancy
✍ Aldo Rescigno; James S. Beck; H. Joseph Goren 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 591 KB

Measurements of the binding of ligand to receptors that are macromolecules, either free or components of biomembranes, often show deviation from what is expected of a simple reaction described by an association and a dissociation rate constant. A more versatile model and more discriminating experime