Determination of daunorubicin, doxorubicin and their fluorescent metabolites by high-pressure liquid chromatography: Plasma levels in DBA2mice
โ Scribed by R. Baurain; D. Deprez-De Campeneere; A. Trouet
- Book ID
- 112285916
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 283 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0344-5704
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Serum and plasma uridine levels in mice, rats, and humans were conveniently measured by reverse-phase high-pressure liquid chromatography. Human serum levels were in the range of 1.9 to 8.4 nmoliml. rat serum levels ranged from 3.7 to 9.4 nmoliml, and mouse serum levels measured 8.0 to 11.8 nmoliml.
A method for the determination of doxorubicin and daunorubicin in plasma is described. The plasma is injected directly into a loop column and then washed with water. After switching the injection valve, the sample is separated on a phenyl column using detection at 254 nm. The detection limit is 10 n