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Determination of cyclic guanosine- and cyclic adenosine monophosphate (cGMP and cAMP) in human plasma and animal tissues by solid phase extraction on silica and liquid chromatography–triple quadrupole mass spectrometry

✍ Scribed by Thomas Van Damme; Yanhua Zhang; Frédéric Lynen; Pat Sandra


Book ID
119289318
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
371 KB
Volume
909
Category
Article
ISSN
1873-376X

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## Abstract A rapid and high‐throughput isotope dilution LC‐MS/MS method with online sample pre‐concentration and clean‐up using anionic mixed‐mode SPE was described for the determination of closantel and rafoxanide in edible bovine and ovine tissues. Tissue samples were extracted with acetonitrile