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Determination of clonality in myelodysplasia by polymerase chain reaction

✍ Scribed by H. van Kamp; W.E. Fibbe; R. Jansen; R. Mout; H.L. Haak; R. Willemze; J.E. Landegent


Book ID
113239503
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
141 KB
Volume
15
Category
Article
ISSN
0145-2126

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## BACKGROUND. Polymerase chain reaction (PCR) based assays are becoming more reliable, simpler, and faster alternatives to traditional Southern blot hybridization (SBH) analysis for the detection of clonal immunoglobulin heavy chain (IgH) gene rearrangements. However, a variety of technical approa