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Determination of butenafine hydrochloride in human plasma by liquid chromatography electrospray ionization-mass spectrometry following its topical administration in human subjects

✍ Scribed by Lin Song; Xuehua Jiang; Ling Wang

Book ID
116620582
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
443 KB
Volume
879
Category
Article
ISSN
1873-376X

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## Abstract A rapid, sensitive and specific high‐performance liquid chromatography–electrospray ionization mass spectrometry (LC‐ESI‐MS) method has been developed and validated for the determination of oxatomide in human plasma. Flunarizine hydrochloride was employed as the internal standard (IS).