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Determination of brain nitric oxide synthase inhibition in vivo: Eex vivo assays of nitric oxide synthase can give incorrect results

โœ Scribed by M. Salter; C. Duffy; R. Hazelwood


Book ID
116037628
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
1006 KB
Volume
34
Category
Article
ISSN
0028-3908

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The flux control coefficient of nitric oxide synthase (NOS), for the in vivo synthesis of the key biological mediator nitric oxide (NO), was determined in four rat brain regions with varying NOS activities (cerebral cortex, hippocampus, amygdala and cerebellum) using metabolic control theory. Flux c