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Determination of bovine alpha S1-casein alleles B and C by allele-specific polymerase chain reaction

โœ Scribed by P. Schlee; O. Rottmann


Book ID
115142921
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
285 KB
Volume
109
Category
Article
ISSN
0931-2668

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Alpha-1 -antitrypsin (A1 AT) deficiency is an autosomal hereditary disorder with a reduction in serum A1 AT levels. In a large family, we used a polymerase chain reaction (PCR)- mediated, site-directed mutagenesis assay to detect the two most common AlAT deficient variants, Z and S. By coamplificati