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Determination of aspartate aminotransferase isoenzymes in hepatic diseases — preliminary findings

✍ Scribed by M. Panteghini; F. Falsetti; E. Chiari; A. Malchiodi

Book ID
115824212
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
532 KB
Volume
128
Category
Article
ISSN
0009-8981

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Hepatic activity and mRNA expression of
Hepatic activity and mRNA expression of aspartate aminotransferase isoenzymes in alcoholic and nonalcoholic liver disease
✍ Stanislas Pol; Bertrand Nalpas; Anne Vassault; Bernadette Bousquet-Lemercier; Do 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 707 KB

In liver and serum, AST activity is dependent on two isoenzymes, which are mitochondrial and cytosolic in nature. In an attempt to explain the well-known increase of serum mitochondrial AST-to-total AST ratio in chronic alcoholism (which is due to a specific increase of the mitochondrial isoenzyme),