Determination of 17β-hydroxy-1α-methyl-17α-propyl-5-α-androstan-3-one in plasma by gas chromatography-mass spectrometry with single-ion detection

Studies on neurosteroids XXIV. Determina

Studies on neurosteroids XXIV. Determination of neuroactive androgens, androsterone and 5α-androstane-3α,17β-diol, in rat brain and serum using liquid chromatography–tandem mass spectrometry

✍ Tatsuya Higashi; Hiroyuki Yokoi; Yukiko Nagura; Tadashi Nishio; Kazutake Shimada 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 247 KB

## Abstract The development and validation of liquid chromatography–electrospray ionization–tandem mass spectrometric (LC–ESI‐MS/MS) methods that enable the quantification of neuroactive androgens, androsterone (5__α__‐androstan‐3__α__‐ol‐17‐one, 3__α__,5__α__‐A) and 5__α__‐androstane‐3__α__,17__β_